Clinico-genomic Decision Support System for Precision Diagnostics and Management

نویسندگان

  • Anuja Kench
  • Vandana Pursnani Janeja
  • Amanda Niskar
  • Yelena Yesha
  • Naphtali Rishe
چکیده

The focus of this work is clinico-genomic decision support system for better diagnosing and managing chronic diseases. We propose a clinical decision support system for early diagnosis of chronic diseases(such as arthritis, Diabetes, Cardio Vascular Disease) and better disease management. We propose a generalizable framework, which can accommodate several distinct features coming into the system from clinical, genomic, environmental domains among others. We utilize this framework to discover similar patients and overlaps among patients in a set of these features which has several applications such as : (a) better cohort discovery for clinical trials, (b) better disease management by studying peer group of patients with similar diagnosis and better prognosis, (c) early disease diagnosis by studying similar features in patients with existing diagnosis

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تاریخ انتشار 2015